Genetic Differences Influence Susceptibility

  •  HLA (Human Leukocyte Antigen) Differences
    • Immune system genetics
    • Affect the processing and recognition of antigens
  • Other
    • Possibly Glutathione Pathway
    • Possibly Transforming Growth Factor Beta 1
    • Others yet undiscovered
  •  Exposome
    • Sum-total of toxins and stressors to which one’s body has been exposed
    •  Presence of multiple toxins amplifies the effects of each… 1+1=3
    •  Includes psychosocial stressors which affect body’s balance

 

  • Types of Mold and Mycotoxins
    • Outdoor molds tend to trigger more allergic responses
      •  Their toxins blow away in the wind without accumulating
    •  Indoor molds (those growing in water damaged building) produce more toxins
      •  These volatile toxins accumulate in the building
      •  Humans breathe them in
    •  Molds toxins are called mycotoxins
      •  They come in many shapes and sizes
      •  They each cause different bodily responses.